2. Mexico City, Mexico
Mexico City has so much to offer everyone who wants to have an amazing vacation in Latin America. Many same sex couples can be seen throughout the city holding hands and the city is quite open to alternative lifestyles. The city is home to Calle Amberes, a club and restaurant run by a gay couple. It is a must see when visiting Mexico. Other popular sights to see while in Mexico City include bull fights and the local markets. You may also enjoy some of the shopping districts where you can find just about anything.